Nutritional interventions to augment resistance training-induced skeletal muscle hypertrophy

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Nutritional interventions to augment resistance training-induced skeletal muscle hypertrophy

Skeletal muscle mass is regulated by a balance between muscle protein synthesis (MPS) and muscle protein breakdown (MPB). In healthy humans, MPS is more sensitive (varying 4-5 times more than MPB) to changes in protein feeding and loading rendering it the primary locus determining gains in muscle mass. Performing resistance exercise (RE) followed by the consumption of protein results in an augm...

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Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men.

BACKGROUND Considerable discrepancy exists in the literature on the proposed benefits of protein supplementation on the adaptive response of skeletal muscle to resistance-type exercise training in the elderly. OBJECTIVE The objective was to assess the benefits of timed protein supplementation on the increase in muscle mass and strength during prolonged resistance-type exercise training in hea...

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Nutritional modulation of training-induced skeletal muscle adaptations.

Skeletal muscle displays remarkable plasticity, enabling substantial adaptive modifications in its metabolic potential and functional characteristics in response to external stimuli such as mechanical loading and nutrient availability. Contraction-induced adaptations are determined largely by the mode of exercise and the volume, intensity, and frequency of the training stimulus. However, eviden...

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A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

PGC-1α is a transcriptional coactivator induced by exercise that gives muscle many of the best known adaptations to endurance-type exercise but has no effects on muscle strength or hypertrophy. We have identified a form of PGC-1α (PGC-1α4) that results from alternative promoter usage and splicing of the primary transcript. PGC-1α4 is highly expressed in exercised muscle but does not regulate mo...

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Ribosome biogenesis adaptation in resistance training-induced human skeletal muscle hypertrophy.

Resistance training (RT) has the capacity to increase skeletal muscle mass, which is due in part to transient increases in the rate of muscle protein synthesis during postexercise recovery. The role of ribosome biogenesis in supporting the increased muscle protein synthetic demands is not known. This study examined the effect of both a single acute bout of resistance exercise (RE) and a chronic...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2015

ISSN: 1664-042X

DOI: 10.3389/fphys.2015.00245